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Pythons kill their prey by the process of constriction, whereby they grasp the prey animal in their teeth to restrain it, while quickly wrapping a number of coils around the body of the prey. Then by applying only sufficient pressure to prevent the prey animal from being able to breathe in, ultimately causing it to succumb because of asphyxia. The prey animal might also suffer some restriction to circulation during constriction, particularly where the snake's coils are wrapped around the animal's neck, but this is not usually fatal as death typically occurs much sooner due to asphyxiation.
Pythons, like the closely related boas, are constrictors and are all, by definition, non-venomous. Most pythons feed on warm-blooded prey such as birds and mammals, but some are known to eat reptiles (including other snake species), amphibians and fish.
Pythons do not, as popularly believed, crush or squeeze their prey to death, and when constricting normal sized prey, the snake will almost certainly never apply enough pressure to break bones.
Larger pythons will usually eat something about the size of a house cat, but larger food items are not unknown (some large Asian species have been known to take down adult Deer, and the African Rock Python has been documented preying upon Gazelle). Pythons swallow their prey whole, and take several days or even weeks to fully digest it. Despite their intimidating size and muscular power, they are generally not dangerous to humans.
Most pythons have rows of heat-sensing organs along their lower lips (labial pits). These pits enable the python to detect objects that are hotter than the surrounding environment with great accuracy, and enable hunting to take place in total darkness, such as inside caves. Pythons that do not have heat-sensing organs identify their prey by smell. Pythons are ambush predators: they typically stay in a camouflaged position and then suddenly strike at passing prey.
Pythons will not usually attack humans unless startled or provoked, although females protecting their eggs can be aggressive. While a very large adult python could possibly kill a human being, humans are generally well outside the normal size range for prey. Reports of python attacks on humans are extremely rare. Despite this, pythons have been aggressively hunted, driving some species (like the Indian Python) to the brink of extinction.

Cold-blooded organisms maintain their body temperatures in ways different from mammals and birds. The term is now outdated in scientific contexts. Cold-blooded creatures were, initially, presumed to be incapable of maintaining their body temperatures at all. They were presumed to be "slaves" to their environments. Whatever the environmental temperature was, so too was their body temperature. Cold-blooded animals are now called ectotherms, for the term cold-blooded is misleading.
Since that time, advances in the study of how creatures maintain their internal temperatures (termed: Thermophysiology) have shown that many of the earlier notions of what the terms "warm-blooded" and "cold-blooded" mean, were far from accurate (see below: breaking down cold-bloodedness). Today scientists realize that body temperature types are not a simple matter of black and white. Most creatures fit more in line with a graded spectrum from one extreme (cold-blooded) to another (warm-blooded).

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